{"id":9423,"date":"2021-10-28T05:27:35","date_gmt":"2021-10-28T03:27:35","guid":{"rendered":"https:\/\/thesmartcityjournal.cibeles.net\/sin-categoria\/harmony-alliance-creates-the-first-european-map-of-hematologic-neoplasms-applying-big-data-and-artificial-intelligence\/"},"modified":"2021-10-27T19:52:59","modified_gmt":"2021-10-27T17:52:59","slug":"harmony-alliance-creates-the-first-european-map-of-hematologic-neoplasms-applying-big-data-and-artificial-intelligence","status":"publish","type":"post","link":"https:\/\/www.thesmartcityjournal.com\/en\/smart-health\/harmony-alliance-creates-the-first-european-map-of-hematologic-neoplasms-applying-big-data-and-artificial-intelligence","title":{"rendered":"HARMONY Alliance creates the first European map of hematologic neoplasms applying big data and artificial intelligence"},"content":{"rendered":"

The Alliance is applying advanced analytical technologies, big data and artificial intelligence, developed by GMV, to draw the first European map of blood tumors<\/em><\/p>\n

In conjunction with World Myelodysplastic Syndromes (MDS) Day<\/strong>, the HARMONY Alliance<\/strong> highlights the progress made in this field through the collaboration of European public centers and pharmaceutical laboratories. The Alliance is comprised of the HARMONY<\/strong> and HARMONY PLUS<\/strong> projects, formalized within the framework of the European Union<\/strong>\u2019s Innovative Medicines Initiative<\/strong> (IMI).<\/em><\/p>\n

<\/em>Five years into the project, nearly 12,000 MDS patient data have been collected, of 40% of which have come from the database of the Spanish Myelodysplastic Syndromes Group (GESMD)<\/strong>, the largest registry of MDS patients in Spain, which chares the vision and values of the HARMONY Alliance<\/strong>.<\/p>\n

Leveraging this extraordinary volume of data leads to the generation of new knowledge, thanks to the capabilities of digital tools such as big data or new artificial intelligence (AI) techniques to improve the analytical capacity and increase precision in research. A clear example is the research project to determine prognostic factors that help identify patients with MDS who are most likely to respond to treatment with hypomethylating agents, as well as experiencing a prolonged response duration. The same analysis is conducted for high-risk patients who can receive intensive chemotherapy. But it is not the only one. The Alliance has a significant portfolio of research projects in at a variety of stages of development in other blood-related diseases.<\/p>\n

Led by two Spaniards, Doctor Jes\u00fas Mar\u00eda Hern\u00e1ndez, a specialist from the Hematology Service<\/strong> at the University Hospital in Salamanca, and Doctor Guillermo Sanz, Clinical Hematology Section Chief at La Fe University Hospital in Valencia<\/strong>, the HARMONY Alliance<\/strong> encompasses the research efforts of over 150 experts in hematologic neoplasms, from more than 80 public-private organizations in 18 European countries.<\/p>\n

The pan-European health research hub was revalidated by the European authorities with the approval of the HARMONY PLUS<\/strong> project in October 2020. This second project extends the scope of action of the Alliance to all hematologic neoplasms and studies the blood diseases not included in the HARMONY<\/strong> project, such as myeloproliferative neoplasms (MPN)\u2013including chronic myeloid leukemia (CML), polycythemia vera (PV), essential thrombocythemia (ET), and myelofibrosis (MF)\u2013, lymphoproliferative disorders, including Hodgkin lymphoma (HL), Waldenstr\u00f6m’s macroglobulinemia, and others. GMV<\/a>,<\/strong> as the project\u2019s technology partner, revalidates the trust of the Alliance to accelerate, through the use of big data, the development of more effective treatments for the clinical approach to patients with blood cancers.<\/p>\n

First European map of blood tumors<\/h2>\n

As Dr. Sanz explains<\/strong>, \u201cwith the HARMONY big data<\/a><\/strong> platform developed by GMV<\/a> Alliance<\/strong> researchers can draw the first European map of blood tumors<\/strong>,using the harmonization of shared data, guaranteeing the protection and privacy of patients at all times.\u201d<\/p>\n

The end goal of the HARMONY Alliance<\/strong> is to reduce the development and market times for new treatments and innovative medicines, to apply precision medicine and move forward toward achieving personalized therapies. \u201cWe have achieved a sufficiently broad sample that includes cases from throughout Europe, which we can use to extract the necessary clinical evidence,\u201d says Hern\u00e1ndez, coordinator of the HARMONY consortium<\/strong>. Dr. Sanz<\/strong>, the co-coordinator, also says that \u201cthis initiative will facilitate decision-making at the health and care policy level to offer more effective and safer treatments.\u201d<\/p>\n

According to Inmaculada P\u00e9rez Garro, GMV\u2019s Digital Health Director<\/strong>, digital technology has played a very relevant role in all of this, as \u201cwe have been able to guarantee observance of all legislation protecting personal health information and extract extraordinary amounts of information that, without these technologies, would have been impossible to manage.\u201d<\/p>\n

Dr. Hern\u00e1ndez<\/strong> points out that \u201cto put together the sample we needed to ensure our research offered conclusive results, we undertook a titanic negotiation effort, bringing together all stakeholders involved in treating blood diseases: patient associations, academic institutions, hospitals, the pharmaceutical industry, regulators, evaluators, and healthcare technology companies. With that, we have been able to collect data on over 80,000 patients with different hematologic neoplasms, including the nearly 12,000 related to MDS patients.\u201d<\/p>\n

The HARMONY Alliance<\/strong> also seeks to cross European borders and extend the study period: blood diseases are very diverse and some of them require follow-up in excess of 15 years. \u201cWe are achieving this in our myeloma database, with an average follow-up of 10 years, making it a unique series,\u201d says Dr. Hern\u00e1ndez Rivas<\/strong>.<\/p>\n

At the same time, \u201cif in the coming years we were able to get the EMA to accept studies like the ones we are conducting in the HARMONY Alliance, it would enable us to conduct trials with new drugs in a single branch that could be compared with the standard, streamlining the availability of new drugs,\u201d Dr. Sanz<\/strong> concludes.<\/p>\n

GMV<\/strong> is a privately-owned technology business group founded in 1984 and trading on a worldwide scale in the following sectors: Aerospace, Defense and Security, Cybersecurity, Intelligent Transportation Systems, Automotive, Healthcare, Telecommunications and IT for government authorities and major corporations. In 2020, it had revenues of nearly 260 million euros. Working with a staff of over 2,300, the company now runs subsidiaries in Spain, USA, Germany, France, Poland, Portugal, Romania, UK, The Netherlands, Belgium, Malaysia and Colombia.<\/p>\n

Seventy-five percent of its turnover comes from international projects on all five continents. The company’s growth strategy is based on continuous innovation and it plows back 10% of its turnover into in-house R&D. GMV has reached CMMI level 5, the world’s most prestigious model in terms of enhancing an organization\u2019s process capability, and it has numerous international patents. Currently, GMV is the world’s number-one independent supplier of ground control systems for commercial telecommunications satellite operators and the European leader in the ground segment of Global Navigation Satellite Systems (EGNOS and Galileo).<\/p>\n

It is also the primary provider of C41 command and control systems for the Spanish Army and the leading national provider of telematic systems for public transport. For over 15 years now it has also been a tried-and-trusted provider of telematics software, services and systems in the automotive sector. In the ICT sector it has become a national benchmark as a provider of advanced cybersecurity solutions and services for IP networks, ICT applications and mobility applications for governments and the development of e-Administration.<\/p><\/p>\n","protected":false},"excerpt":{"rendered":"

The Alliance is applying advanced analytical technologies, big data and artificial intelligence, developed by GMV, to draw the first European map of blood tumors In conjunction with World Myelodysplastic Syndromes (MDS) Day, the HARMONY Alliance highlights the progress made in this field through the collaboration of European public centers and pharmaceutical laboratories. The Alliance is\u2026<\/p>\n","protected":false},"author":2,"featured_media":9407,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_scj_primary_category_id":88,"_scj_featured":false,"_scj_featured_from":"","_scj_featured_until":"","_scj_featured_order":0,"_scj_visibility_class":"current","_scj_layout_family":"standard","_scj_article_style":"","_scj_display_overrides":[],"_scj_intro_image_id":9407,"_scj_intro_alt":"Creates the first European map of hematologic neoplasms applying big data and artificial intelligence","_scj_intro_caption":"","_scj_intro_class":"","_scj_intro_float":"","_scj_full_image_id":9407,"_scj_full_alt":"Creates the first European map of hematologic neoplasms applying big data and artificial intelligence","_scj_full_caption":"","_scj_full_class":"","_scj_full_float":"","_scj_media_type":"","_scj_media_provider":"","_scj_media_external_id":"","_scj_media_url":"","_scj_media_poster_id":0,"_scj_media_width":0,"_scj_media_height":0,"_scj_media_aspect_ratio":"","_scj_media_description":"","_scj_gallery_items":[],"_scj_related_post_ids":[],"_scj_additional_authors":[],"scj_layout_family":"standard","scj_media_provider":"","scj_media_url":"","scj_full_caption":"","footnotes":""},"categories":[88],"tags":[],"class_list":["post-9423","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-smart-health"],"yoast_head":"\nHARMONY Alliance creates the first European map of hematologic neoplasms applying big data and artificial intelligence - thesmartcityjournal.com<\/title>\n<meta name=\"description\" content=\"In conjunction with World Myelodysplastic Syndromes (MDS) Day, the HARMONY Alliance highlights the progress made in this field through the collaboration of European public centers and pharmaceutical laboratories. 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