{"id":21055,"date":"2026-03-22T11:23:51","date_gmt":"2026-03-22T10:23:51","guid":{"rendered":"https:\/\/thesmartcityjournal.cibeles.net\/sin-categorizar\/pancreas-artificial-implantable-para-la-diabetes-de-tipo-1\/"},"modified":"2026-03-22T11:28:00","modified_gmt":"2026-03-22T10:28:00","slug":"pancreas-artificial-implantable-para-la-diabetes-de-tipo-1","status":"publish","type":"post","link":"https:\/\/www.thesmartcityjournal.com\/es\/investigacion\/pancreas-artificial-implantable-para-la-diabetes-de-tipo-1","title":{"rendered":"P\u00e1ncreas artificial implantable para la diabetes de tipo 1"},"content":{"rendered":"

Un dispositivo totalmente implantable que imita al p\u00e1ncreas podr\u00eda aliviar notablemente la vida de las personas con diabetes de tipo 1<\/span><\/i><\/p>\n

La diabetes de tipo 1 es una enfermedad autoinmunitaria en la que el p\u00e1ncreas ya no puede segregar insulina. Para millones de personas, esto se traduce en medirse la glucemia, controlar el consumo de carbohidratos e inyectarse insulina a diario.<\/span><\/p>\n

Los sistemas h\u00edbridos de circuito cerrado han mejorado considerablemente el control gluc\u00e9mico y la calidad de vida mediante la monitorizaci\u00f3n continua de la glucemia y las bombas de insulina subcut\u00e1neas. Sin embargo, la administraci\u00f3n subcut\u00e1nea sigue siendo sub\u00f3ptima porque la absorci\u00f3n de la insulina es relativamente lenta, lo que requiere una planificaci\u00f3n cuidadosa de las comidas y la intervenci\u00f3n frecuente del paciente.<\/span><\/p>\n

Sistema de administraci\u00f3n intraperitoneal de insulina<\/h2>\n

El equipo del proyecto FORGETDIABETES(se abrir\u00e1 en una nueva ventana), financiado con fondos europeos, propone un planteamiento terap\u00e9utico completamente nuevo: un p\u00e1ncreas bi\u00f3nico totalmente implantable que administra insulina por v\u00eda intraperitoneal.<\/span><\/p>\n

\u00abLa administraci\u00f3n intraperitoneal se asemeja m\u00e1s a la fisiolog\u00eda normal, lo que permite que la insulina act\u00fae y se elimine con m\u00e1s rapidez\u00bb, explica Claudio Cobelli, catedr\u00e1tico em\u00e9rito de Bioingenier\u00eda de la Universidad de Padua y coordinador del proyecto.<\/span><\/p>\n

El sistema integra tres componentes b\u00e1sicos: un sensor de glucemia, un algoritmo de control y una bomba conectada a un dep\u00f3sito interno de insulina. Una caracter\u00edstica novedosa es el uso de una c\u00e1psula oral de insulina(se abrir\u00e1 en una nueva ventana) que los pacientes deben ingerir una vez a la semana. Estas pastillas recorren pasivamente el tracto gastrointestinal hasta llegar al dispositivo implantado, donde rellenan el dep\u00f3sito. Este enfoque reduce la carga psicosocial asociada a las inyecciones frecuentes.<\/span><\/p>\n

Y lo que es m\u00e1s importante, el sistema utiliza nuevos recubrimientos biocompatibles e inmunooptimizados, que garantizan la seguridad y estabilidad a largo plazo. La transmisi\u00f3n continua de datos a la nube garantiza la gesti\u00f3n de las enfermedades.<\/span><\/p>\n

Algoritmos adaptativos para un control preciso de la glucemia<\/h2>\n

En el coraz\u00f3n del sistema se encuentra un avanzado algoritmo de control adaptado a cada paciente. Mantener la glucemia dentro del intervalo objetivo recomendado requiere una dosificaci\u00f3n precisa de la insulina, ya que una dosis demasiado baja puede provocar hiperglucemia y una dosis demasiado alta, hipoglucemia. El algoritmo adaptativo interpreta continuamente los datos de los sensores y ajusta la entrega en consecuencia.<\/span><\/p>\n

Dado que la administraci\u00f3n intraperitoneal imita m\u00e1s al p\u00e1ncreas natural(se abrir\u00e1 en una nueva ventana), los investigadores esperan que con el tiempo pueda permitir objetivos de glucemia m\u00e1s estrictos y una mayor estabilidad metab\u00f3lica. El dispositivo est\u00e1 dise\u00f1ado para responder con rapidez a los cambios que se producen tras las comidas o el ejercicio, lo que reduce la necesidad de una intervenci\u00f3n constante del usuario. Adem\u00e1s, se carga mediante transferencia inal\u00e1mbrica de energ\u00eda desde un parche ponible situado fuera del cuerpo.<\/span><\/p>\n

Fases de prueba y validaci\u00f3n<\/h2>\n

El consorcio ha probado con \u00e9xito el sistema en modelos animales de diabetes. Si es eficaz, la tecnolog\u00eda podr\u00eda reducir considerablemente las numerosas acciones relacionadas con la diabetes que muchos pacientes realizan en la actualidad cada mes y las sustituir\u00eda por unos pocos pasos de mantenimiento.<\/span><\/p>\n

En \u00faltima instancia, la ambici\u00f3n es acercarse a un p\u00e1ncreas artificial automatizado y totalmente implantable que alivie la carga diaria del tratamiento de la enfermedad. Al combinar la administraci\u00f3n fisiol\u00f3gica de insulina con el control inteligente, en FORGETDIABETES se pretende ofrecer a las personas con diabetes de tipo 1 una mayor libertad, un mejor control metab\u00f3lico y una calidad de vida sustancialmente mejor.<\/span><\/p>\n

M\u00e1s all\u00e1 del rendimiento cl\u00ednico, el equipo del proyecto tambi\u00e9n aborda la fiabilidad y la escalabilidad a largo plazo. Cortesi comenta: \u00abLos pr\u00f3ximos pasos incluyen estudios adicionales con animales, la miniaturizaci\u00f3n de los componentes del dispositivo, as\u00ed como el aumento de la compatibilidad y durabilidad del implante seg\u00fan las normas europeas de productos sanitarios\u00bb.<\/span><\/p>\n

A largo plazo, esto acercar\u00e1 la soluci\u00f3n de FORGETDIABETES a la aplicaci\u00f3n cl\u00ednica, lo que facilitar\u00e1 la vida a las personas que padecen diabetes de tipo 1.<\/span><\/p>\n

Imagen: Universidad de Padua<\/span><\/i><\/p>\n","protected":false},"excerpt":{"rendered":"

Un dispositivo totalmente implantable que imita al p\u00e1ncreas podr\u00eda aliviar notablemente la vida de las personas con diabetes de tipo 1 La diabetes de tipo 1 es una enfermedad autoinmunitaria en la que el p\u00e1ncreas ya no puede segregar insulina. Para millones de personas, esto se traduce en medirse la glucemia, controlar el consumo de\u2026<\/p>\n","protected":false},"author":2,"featured_media":21054,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_scj_primary_category_id":97,"_scj_featured":false,"_scj_featured_from":"","_scj_featured_until":"","_scj_featured_order":0,"_scj_visibility_class":"current","_scj_layout_family":"standard","_scj_article_style":"","_scj_display_overrides":[],"_scj_intro_image_id":21054,"_scj_intro_alt":"P\u00e1ncreas artificial implantable para la diabetes de tipo 1","_scj_intro_caption":"","_scj_intro_class":"","_scj_intro_float":"","_scj_full_image_id":21054,"_scj_full_alt":"P\u00e1ncreas artificial implantable para la diabetes de tipo 1","_scj_full_caption":"","_scj_full_class":"","_scj_full_float":"","_scj_media_type":"","_scj_media_provider":"","_scj_media_external_id":"","_scj_media_url":"","_scj_media_poster_id":0,"_scj_media_width":0,"_scj_media_height":0,"_scj_media_aspect_ratio":"","_scj_media_description":"","_scj_gallery_items":[],"_scj_related_post_ids":[],"_scj_additional_authors":[],"scj_layout_family":"standard","scj_media_provider":"","scj_media_url":"","scj_full_caption":"","footnotes":""},"categories":[97],"tags":[3624,3626,246,236,3625,240],"class_list":["post-21055","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-investigacion","tag-diabetes-tipo-1","tag-dispositivos-implantables","tag-innovacion-medica","tag-investigacion-europea","tag-pancreas-artificial","tag-salud-digital"],"yoast_head":"\nP\u00e1ncreas artificial implantable para la diabetes de tipo 1 - thesmartcityjournal.com<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.thesmartcityjournal.com\/es\/investigacion\/pancreas-artificial-implantable-para-la-diabetes-de-tipo-1\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"P\u00e1ncreas artificial implantable para la diabetes de tipo 1 - thesmartcityjournal.com\" \/>\n<meta property=\"og:description\" content=\"Un dispositivo totalmente implantable que imita al p\u00e1ncreas podr\u00eda aliviar notablemente la vida de las personas con diabetes de tipo 1 La diabetes de tipo 1 es una enfermedad autoinmunitaria en la que el p\u00e1ncreas ya no puede segregar insulina. 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